multiple logistic regression analysis by a stepwise forward-conditional procedure Search Results


flow cytometry  (Sony)
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Sony flow cytometry
Flow Cytometry, supplied by Sony, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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flow cytometry - by Bioz Stars, 2026-07
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granexin® gel  (FirstString Research Inc)
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FirstString Research Inc granexin® gel
A: <t>Cx43</t> interacts with many proteins including some (noted here) that have been reported to be involved in tumourigenesis. Cx43 binding proteins are indicated as enhancing (red type), reducing (green type), or playing unclear roles (blue) in tumourigenesis but their mode of action may, in part, be due to their interactions with Cx43. Calmodulin interacts with the intracellular loop, while the others interact with motifs encoded within the C-terminal tail. The names of the Cx43 interactors are positioned near the site of the C-terminal tail where they bind, except TSG101, NOV, β-catenin, BAX, p62, EPS15 and PKC as their specific binding sites within the C-terminal domain are less well defined. A more complete list of Cx43 interactors can be found in other publications 137,295,298. B: Connexins present in gap junctions (primarily Cx26, Cx32, Cx43) have been widely reported to inhibit the promotion, growth and invasion stages of tumourigenesis, but may have more complex roles in later stages of disease progression that is tumour type dependent 3.
Granexin® Gel, supplied by FirstString Research Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multiple+logistic+regression+analysis+by+a+stepwise+forward-conditional+procedure/pmc06461534-247-53-41?v=FirstString+Research+Inc
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granexin® gel - by Bioz Stars, 2026-07
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A: Cx43 interacts with many proteins including some (noted here) that have been reported to be involved in tumourigenesis. Cx43 binding proteins are indicated as enhancing (red type), reducing (green type), or playing unclear roles (blue) in tumourigenesis but their mode of action may, in part, be due to their interactions with Cx43. Calmodulin interacts with the intracellular loop, while the others interact with motifs encoded within the C-terminal tail. The names of the Cx43 interactors are positioned near the site of the C-terminal tail where they bind, except TSG101, NOV, β-catenin, BAX, p62, EPS15 and PKC as their specific binding sites within the C-terminal domain are less well defined. A more complete list of Cx43 interactors can be found in other publications 137,295,298. B: Connexins present in gap junctions (primarily Cx26, Cx32, Cx43) have been widely reported to inhibit the promotion, growth and invasion stages of tumourigenesis, but may have more complex roles in later stages of disease progression that is tumour type dependent 3.

Journal: Nature reviews. Drug discovery

Article Title: Therapeutic strategies targeting connexins

doi: 10.1038/nrd.2018.138

Figure Lengend Snippet: A: Cx43 interacts with many proteins including some (noted here) that have been reported to be involved in tumourigenesis. Cx43 binding proteins are indicated as enhancing (red type), reducing (green type), or playing unclear roles (blue) in tumourigenesis but their mode of action may, in part, be due to their interactions with Cx43. Calmodulin interacts with the intracellular loop, while the others interact with motifs encoded within the C-terminal tail. The names of the Cx43 interactors are positioned near the site of the C-terminal tail where they bind, except TSG101, NOV, β-catenin, BAX, p62, EPS15 and PKC as their specific binding sites within the C-terminal domain are less well defined. A more complete list of Cx43 interactors can be found in other publications 137,295,298. B: Connexins present in gap junctions (primarily Cx26, Cx32, Cx43) have been widely reported to inhibit the promotion, growth and invasion stages of tumourigenesis, but may have more complex roles in later stages of disease progression that is tumour type dependent 3.

Article Snippet: CoDa has been restructured as OcuNexus Therapeutics Inc., and they have taken the development of AsODN (renamed as Nexagon®) forward for multiple applications in conditions affecting the eye that are described later. aCT1 (also known as αCT1, trade name Granexin® gel, FirstString) is a peptide that mimics the last 9 amino acids of Cx43 (AA374–382) preceded by a cell internalization sequence.

Techniques: Binding Assay

Selected connexin-targeted agents currently in clinical trials

Journal: Nature reviews. Drug discovery

Article Title: Therapeutic strategies targeting connexins

doi: 10.1038/nrd.2018.138

Figure Lengend Snippet: Selected connexin-targeted agents currently in clinical trials

Article Snippet: CoDa has been restructured as OcuNexus Therapeutics Inc., and they have taken the development of AsODN (renamed as Nexagon®) forward for multiple applications in conditions affecting the eye that are described later. aCT1 (also known as αCT1, trade name Granexin® gel, FirstString) is a peptide that mimics the last 9 amino acids of Cx43 (AA374–382) preceded by a cell internalization sequence.

Techniques: Modification